Sky Bet League Two
Venue:Rodney ParadeDate:28 MarchKick-off:15:00 BSTCoverage:BBC Sport website, BBC Radio 5 live, BBC Radio Wales, Final Score
Newport will be determined to bounce back from their 1-0 defeat at leaders Northampton on Good Friday.
Manager Warren Feeney felt his team deserved better against the Cobblers after dominating for periods.
Accrington are a point away from the automatic promotion places following their 1-0 win over Leyton Orient.
Neither team will relish the difficult Rodney Parade surface after a Pro12 rugby match was played there on Sunday and heavy rain overnight.