Wales back Hallam Amos will not play for the Newport Gwent Dragons as they entertain Connacht in the Pro12.
Amos was released by Wales for last Friday’s defeat to Ulster, but will not feature at Rodney Parade on Thursday.
He is replaced by wing Nick Scott as one of four changes, while fly-half Jason Tovey returns from a back spasm.
Connacht have made three changes from their win against Scarlets on 30 January, with AJ MacGinty replacing Jack Carty at fly-half.
Craig Ronaldson comes in at inside centre with Bundee Aki switching to 13, while prop Rodney Ah You is recalled.
Ireland Six Nations squad members Kieran Marmion, Finlay Bealham and Ultan Dillane are on the bench.
“Given that they haven’t trained with us this week, they will add impact from the bench,” said head coach Pat Lam.
“We are under no illusions as to how tough the challenge will be in Newport, and in tough conditions.”
Dragons: Geraint Rhys Jones; Ashton Hewitt, Adam Hughes, Adam Warren, Nick Scott; Jason Tovey, Sarel Pretorius; Phil Price, Elliot Dee, Brok Harris, Matthew Screech, Rynard Landman (capt), Ben White, Nic Cudd, Nick Crosswell.
Replacements: Rhys Buckley, Luke Garrett, Shaun Knight, Cory Hill, James Benjamin, Charlie Davies, Angus O’Brien, Ross Wardle.
Connacht: Tiernan O’Halloran; Danie Poolman, Bundee Aki, Craig Ronaldson, Matt Healy; AJ MacGinty, Caolin Blade; Denis Buckley, Tom McCartney, Rodney Ah You, George Naoupu, Aly Muldowney, John Muldoon (capt), Jake Heenan, Eoghan Masterson.
Replacements: Dave Heffernan, Ronan Loughney, Finlay Bealham, Ultan Dillane, Eoin McKeon, Kieran Marmion, Peter Robb, Rory Parata.
Referee: David Wilkinson (IRFU)
Assistant referees: Dan Jones, Simon Rees (both WRU)
Citing commissioner: Jeff Mark (WRU)